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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDM16
All Species:
12.42
Human Site:
S718
Identified Species:
24.85
UniProt:
Q9HAZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ2
NP_071397.2
1276
140251
S718
M
Q
E
K
K
L
G
S
L
P
Y
H
S
A
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093583
1230
138131
P698
Y
P
S
M
F
P
L
P
F
F
P
A
F
S
Q
Dog
Lupus familis
XP_536720
1330
145448
S792
M
Q
E
K
K
L
A
S
L
P
Y
H
S
V
F
Cat
Felis silvestris
Mouse
Mus musculus
A2A935
1275
140840
S719
M
Q
E
K
K
L
G
S
L
P
Y
H
S
V
F
Rat
Rattus norvegicus
XP_002726668
1257
138805
S719
M
Q
E
K
K
L
G
S
L
P
Y
H
S
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508323
979
106177
G471
A
P
N
L
N
H
A
G
L
G
F
N
D
Y
F
Chicken
Gallus gallus
XP_417551
908
100815
N400
K
C
E
S
S
L
E
N
S
Y
L
E
K
L
K
Frog
Xenopus laevis
B7ZRU9
1055
118966
Q547
P
K
E
T
K
K
V
Q
K
G
K
T
E
S
P
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
P645
E
I
K
P
L
P
P
P
P
S
K
P
A
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7Z8
990
109209
P482
P
P
F
L
P
Q
N
P
L
H
P
T
N
I
P
Honey Bee
Apis mellifera
XP_001121599
1541
171480
E887
P
Y
K
C
K
Y
C
E
R
S
F
S
I
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
F1200
P
A
A
S
E
L
P
F
M
K
N
G
S
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
53.9
83.4
N.A.
88.2
86.2
N.A.
57.1
59.9
45.4
61.2
N.A.
27.5
21.8
N.A.
20.8
Protein Similarity:
100
N.A.
68
87.8
N.A.
91.8
90.1
N.A.
62.1
64.5
57.2
71.9
N.A.
39.9
35.3
N.A.
35.8
P-Site Identity:
100
N.A.
0
86.6
N.A.
93.3
93.3
N.A.
13.3
13.3
13.3
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
6.6
86.6
N.A.
93.3
93.3
N.A.
26.6
20
26.6
13.3
N.A.
13.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
17
0
0
0
0
9
9
9
0
% A
% Cys:
0
9
0
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
0
50
0
9
0
9
9
0
0
0
9
9
0
9
% E
% Phe:
0
0
9
0
9
0
0
9
9
9
17
0
9
0
42
% F
% Gly:
0
0
0
0
0
0
25
9
0
17
0
9
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
9
0
34
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
9
9
17
34
50
9
0
0
9
9
17
0
9
0
9
% K
% Leu:
0
0
0
17
9
50
9
0
50
0
9
0
0
17
0
% L
% Met:
34
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
9
9
0
0
9
9
9
0
0
% N
% Pro:
34
25
0
9
9
17
17
25
9
34
17
9
0
0
25
% P
% Gln:
0
34
0
0
0
9
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
9
17
9
0
0
34
9
17
0
9
42
34
9
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
9
0
0
0
9
34
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _